Combination of a STAT3 Inhibitor and an mTOR Inhibitor Against a Temozolomide-resistant Glioblastoma Cell Line

Background: Temozolomide-resistant (TMZ-R) glioblastoma is very difficult to treat, and a novel approach to overcome resistance is needed. Materials and Methods: The efficacy of a combination treatment of STAT3 inhibitor, STX-0119, with rapamycin was investigated against our established TMZ-resistan...

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Veröffentlicht in:Cancer Genomics Proteomics
Hauptverfasser: MIYATA*, HARUO, ASHIZAWA*, TADASHI, IIZUKA, AKIRA, KONDOU, RYOTA, NONOMURA, CHIZU, SUGINO, TAKASHI, URAKAMI, KENICHI, ASAI, AKIRA, HAYASHI, NAKAMASA, MITSUYA, KOICHI, NAKASU, YOKO, YAMAGUCHI, KEN, AKIYAMA, YASUTO
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Institute of Anticancer Research 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267503/
https://ncbi.nlm.nih.gov/pubmed/28031240
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