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Rotor termination is critically dependent on kinetic properties of I kur inhibitors in an in silico model of chronic atrial fibrillation.
Inhibition of the atrial ultra-rapid delayed rectifier potassium current (I Kur) represents a promising therapeutic strategy in the therapy of atrial fibrillation. However, experimental and clinical data on the antiarrhythmic efficacy remain controversial. We tested the hypothesis that antiarrhythmi...
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Autors principals: | , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science (PLoS)
2013-01-01
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Col·lecció: | PLoS ONE |
Accés en línia: | http://europepmc.org/articles/PMC3869770?pdf=render |
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