Ploidy reductions in murine fusion-derived hepatocytes.

We previously showed that fusion between hepatocytes lacking a crucial liver enzyme, fumarylacetoacetate hydrolase (FAH), and wild-type blood cells resulted in hepatocyte reprogramming. FAH expression was restored in hybrid hepatocytes and, upon in vivo expansion, ameliorated the effects of FAH defi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Andrew W Duncan, Raymond D Hickey, Nicole K Paulk, Andrew J Culberson, Susan B Olson, Milton J Finegold, Markus Grompe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2009-02-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC2636893?pdf=render
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi