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Cationic Amphipathic Antimicrobial Peptides Perturb the Inner Membrane of Germinated Spores Thus Inhibiting Their Outgrowth

The mode of action of four cationic amphipathic antimicrobial peptides (AMPs) was evaluated against the non-pathogenic, Gram-positive, spore-forming bacterium, Bacillus subtilis. The AMPs were TC19, TC84, BP2, and the lantibiotic Nisin A. TC19 and TC84 were derived from the human thrombocidin-1. Bac...

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Bibliografiske detaljer
Main Authors: Soraya Omardien, Jan Wouter Drijfhout, Sebastian A. Zaat, Stanley Brul
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-09-01
Serier:Frontiers in Microbiology
Fag:
Online adgang:https://www.frontiersin.org/article/10.3389/fmicb.2018.02277/full
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