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Cationic Amphipathic Antimicrobial Peptides Perturb the Inner Membrane of Germinated Spores Thus Inhibiting Their Outgrowth

The mode of action of four cationic amphipathic antimicrobial peptides (AMPs) was evaluated against the non-pathogenic, Gram-positive, spore-forming bacterium, Bacillus subtilis. The AMPs were TC19, TC84, BP2, and the lantibiotic Nisin A. TC19 and TC84 were derived from the human thrombocidin-1. Bac...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Omardien, Soraya, Drijfhout, Jan Wouter, Zaat, Sebastian A., Brul, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168669/
https://ncbi.nlm.nih.gov/pubmed/30319583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02277
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