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Cholesterol Contributes to Diabetic Nephropathy through SCAP-SREBP-2 Pathway

Diabetic nephropathy (DN) has been associated with the presence of lipid deposition. We hypothesized that the disruption of intracellular cholesterol feedback may contribute to DN. Diabetes was induced by high fat/sucrose diet and low-dose intraperitoneal injection of streptozocin (STZ) in male Spra...

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Detalhes bibliográficos
Main Authors: Hong Sun, Yang Yuan, Zi-Lin Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2013-01-01
Colecção:International Journal of Endocrinology
Acesso em linha:http://dx.doi.org/10.1155/2013/592576
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