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Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.
To better understand off-target effects of widely prescribed psychoactive drugs, we performed a comprehensive series of chemogenomic screens using the budding yeast Saccharomyces cerevisiae as a model system. Because the known human targets of these drugs do not exist in yeast, we could employ the y...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2008-08-01
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| Серии: | PLoS Genetics |
| Online-ссылка: | http://europepmc.org/articles/PMC2483942?pdf=render |
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