SUPPRESSION OF SUBGENOMIC HEPATITIS C VIRUS RNA REPLICON REPLICATION IN Huh-7 CELLS BY THE NS3 PROTEASE INHIBITOR SCH5030334: A STOCHASTIC MATHEMATICAL MODEL

Hepatitis C virus (HCV) causes a severe liver disease frequentlyassociatedwith cirrhosis andhepatocellular carcinoma. No effective anti-HCVtherapyis available so far. Thus, it is pertinent to applymathematical modelingto prediction ofthe efficiencyofnew candidate pharmaceuticals. Astochastic mathema...

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Hauptverfasser: E. L. Mishchenko, N. V. Ivanisenko, I. R. Akberdin, P. S. Demenkov, V. A. Likhoshvai, N. A. Kolchanov, V. A. Ivanisenko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2014-12-01
Schriftenreihe:Vavilovskij Žurnal Genetiki i Selekcii
Schlagworte:
hepatitis c virus
subgenomic replicon
mathematical modeling
effectiveness of drugs
Online Zugang:https://vavilov.elpub.ru/jour/article/view/50
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