A New Stochastic Model for Subgenomic Hepatitis C Virus Replication Considers Drug Resistant Mutants

As an RNA virus, hepatitis C virus (HCV) is able to rapidly acquire drug resistance, and for this reason the design of effective anti-HCV drugs is a real challenge. The HCV subgenomic replicon-containing cells are widely used for experimental studies of the HCV genome replication mechanisms, for dru...

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Detalhes bibliográficos
Main Authors: Ivanisenko, Nikita V., Mishchenko, Elena L., Akberdin, Ilya R., Demenkov, Pavel S., Likhoshvai, Vitaly A., Kozlov, Konstantin N., Todorov, Dmitry I., Gursky, Vitaly V., Samsonova, Maria G., Samsonov, Alexander M., Clausznitzer, Diana, Kaderali, Lars, Kolchanov, Nikolay A., Ivanisenko, Vladimir A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958367/
https://ncbi.nlm.nih.gov/pubmed/24643004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091502
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