Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis

BACKGROUND: Irinotecan (IRI) is an integral part of colorectal cancer (CRC) therapy, but response rates are unsatisfactory and resistance mechanisms are still insufficiently understood. As fibroblast growth factor receptor 3 (FGFR3) mediates essential survival signals in CRC, it is a candidate gene...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Zeynep N. Erdem, Stefanie Schwarz, Daniel Drev, Christine Heinzle, Andrea Reti, Petra Heffeter, Xenia Hudec, Klaus Holzmann, Bettina Grasl-Kraupp, Walter Berger, Michael Grusch, Brigitte Marian
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2017-06-01
Серии:Translational Oncology
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1936523317300220
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы