Phosphorus containing analogues of SAHA as inhibitors of HDACs

Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets. Vorinostat, or suberanilohydroxamic acid (SAHA), is an histone deac...

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Detaylı Bibliyografya
Asıl Yazarlar: Michael D. Pun, Hsin-Hua Wu, Feyisola P. Olatunji, Britany N. Kesic, John W. Peters, Clifford E. Berkman
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis Group 2022-12-01
Seri Bilgileri:Journal of Enzyme Inhibition and Medicinal Chemistry
Konular:
HDAC
phosphate
phosphoramidate
phosphorothiolate
SAHA
Online Erişim:https://www.tandfonline.com/doi/10.1080/14756366.2022.2063281
Etiketler: Etiketle
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