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Phosphorus containing analogues of SAHA as inhibitors of HDACs
Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets. Vorinostat, or suberanilohydroxamic acid (SAHA), is an histone deac...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis Group
2022-12-01
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| Seria: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.tandfonline.com/doi/10.1080/14756366.2022.2063281 |
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