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Phosphorus containing analogues of SAHA as inhibitors of HDACs

Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets. Vorinostat, or suberanilohydroxamic acid (SAHA), is an histone deac...

詳細記述

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書誌詳細
主要な著者: Michael D. Pun, Hsin-Hua Wu, Feyisola P. Olatunji, Britany N. Kesic, John W. Peters, Clifford E. Berkman
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis Group 2022-12-01
シリーズ:Journal of Enzyme Inhibition and Medicinal Chemistry
主題:
オンライン・アクセス:https://www.tandfonline.com/doi/10.1080/14756366.2022.2063281
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