Phosphorus containing analogues of SAHA as inhibitors of HDACs

Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets. Vorinostat, or suberanilohydroxamic acid (SAHA), is an histone deac...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Michael D. Pun, Hsin-Hua Wu, Feyisola P. Olatunji, Britany N. Kesic, John W. Peters, Clifford E. Berkman
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis Group 2022-12-01
סדרה:Journal of Enzyme Inhibition and Medicinal Chemistry
נושאים:
HDAC
phosphate
phosphoramidate
phosphorothiolate
SAHA
גישה מקוונת:https://www.tandfonline.com/doi/10.1080/14756366.2022.2063281
תגים: הוספת תג
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