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Phosphorus containing analogues of SAHA as inhibitors of HDACs

Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets. Vorinostat, or suberanilohydroxamic acid (SAHA), is an histone deac...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Michael D. Pun, Hsin-Hua Wu, Feyisola P. Olatunji, Britany N. Kesic, John W. Peters, Clifford E. Berkman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis Group 2022-12-01
Cyfres:Journal of Enzyme Inhibition and Medicinal Chemistry
Pynciau:
Mynediad Ar-lein:https://www.tandfonline.com/doi/10.1080/14756366.2022.2063281
Tagiau: Ychwanegu Tag
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