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Computational Analysis of the Binding Specificities of PH Domains

Pleckstrin homology (PH) domains share low sequence identities but extremely conserved structures. They have been found in many proteins for cellular signal-dependent membrane targeting by binding inositol phosphates to perform different physiological functions. In order to understand the sequence-s...

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Autores principales: Zhi Jiang, Zhongjie Liang, Bairong Shen, Guang Hu
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Limited 2015-01-01
Colección:BioMed Research International
Acceso en línea:http://dx.doi.org/10.1155/2015/792904
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