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IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice.
The availability of a highly purified and well characterized circumsporozoite protein (CSP) is essential to improve upon the partial success of recombinant CSP-based malaria vaccine candidates. Soluble, near full-length, Plasmodium falciparum CSP vaccine antigen (CS/D) was produced in E. coli under...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Public Library of Science (PLoS)
2014-01-01
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叢編: | PLoS ONE |
在線閱讀: | http://europepmc.org/articles/PMC4208815?pdf=render |
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