Artemether resistance <it>in vitro</it> is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with <it>Plasmodium falciparum</it> infections

<p>Abstract</p> <p>Background</p> <p>Monitoring resistance phenotypes for <it>Plasmodium falciparum</it>, using <it>in vitro</it> growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resis...

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Main Authors: Pillai Dylan R, Lau Rachel, Khairnar Krishna, Lepore Rosalba, Via Allegra, Staines Henry M, Krishna Sanjeev
Format: Artigo
Jezik:Inglês
Izdano: BMC 2012-04-01
Serija:Malaria Journal
Teme:
Artemisinin resistance
<it>pfmdr1</it>
<it>pfatp6</it>
Gene copy number
Malaria
Travellers
<it>Plasmodium</it>
Online dostop:http://www.malariajournal.com/content/11/1/131
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