Recombinant <i>Bacillus caldovelox</i> Arginase Mutant (BCA-M) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition in Human Cervical Cancer Cells

With our recent success in developing a recombinant human arginase drug against broad-spectrum cancer cell lines, we have explored the potential of a recombinant <i>Bacillus caldovelox</i> arginase mutant (BCA-M) for human cervical cancer treatment. Our studies demonstrated that BCA-M si...

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Detalhes bibliográficos
Main Authors: Sai-Fung Chung, Chi-Fai Kim, Ho-Yin Chow, Hiu-Chi Chong, Suet-Ying Tam, Yun-Chung Leung, Wai-Hung Lo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-10-01
Colecção:International Journal of Molecular Sciences
Assuntos:
apoptosis
arginase
autophagy
cell cycle arrest
cervical cancer cell
Acesso em linha:https://www.mdpi.com/1422-0067/21/20/7445
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