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Estimating linkage disequilibrium from genotypes under Hardy-Weinberg equilibrium

Abstract Background Measures of linkage disequilibrium (LD) play a key role in a wide range of applications from disease association to demographic history estimation. The true population LD cannot be measured directly and instead can only be inferred from genetic samples, which are unavoidably subj...

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書目詳細資料
Main Authors: Tin-Yu J. Hui, Austin Burt
格式: Artigo
語言:Inglês
出版: BMC 2020-02-01
叢編:BMC Genetics
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在線閱讀:http://link.springer.com/article/10.1186/s12863-020-0818-9
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