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Estimating linkage disequilibrium from genotypes under Hardy-Weinberg equilibrium
Abstract Background Measures of linkage disequilibrium (LD) play a key role in a wide range of applications from disease association to demographic history estimation. The true population LD cannot be measured directly and instead can only be inferred from genetic samples, which are unavoidably subj...
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Main Authors: | , |
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格式: | Artigo |
語言: | Inglês |
出版: |
BMC
2020-02-01
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叢編: | BMC Genetics |
主題: | |
在線閱讀: | http://link.springer.com/article/10.1186/s12863-020-0818-9 |
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