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The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis

Abstract Background Age-related macular degeneration (AMD) is a multifactorial chronic disease of the eye. Several candidate pathways have been hypothesized to play a role in AMD pathogenesis. Our work and those of others suggests inflammasome activity as a mechanism associated with retinal pigment...

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Bibliografische gegevens
Hoofdauteurs: Jiangyuan Gao, Jing Z. Cui, Aikun Wang, Hao Hang Rachel Chen, Alison Fong, Joanne A. Matsubara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2019-08-01
Reeks:Journal of Neuroinflammation
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Online toegang:http://link.springer.com/article/10.1186/s12974-019-1558-5
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