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The alternate GNB3 splice variant, Gβ3s, exhibits an altered signalling response to EGF stimulation, which leads to enhanced cell migration

It has recently been reported that the duplication of the GNB3 gene has been shown to be directly linked to an obesity phenotype, both in humans and also in a humanised mouse model. Moreover, the common human GNB3 c.825C>T polymorphism (rs5443) causes this ubiquitously expressed g...

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Detalhes bibliográficos
Main Authors: Hemanth Tummala, Hilal S Khalil, Mohammad R. Islam, Sarah J. Jones, Ian R. Ellis, Isabella D’Ascanio, Nikolai Zhelev, Douglas H. Lester
Formato: Artigo
Idioma:Inglês
Publicado em: Pensoft Publishers 2013-11-01
Colecção:BioDiscovery
Assuntos:
ERK
AKT
Acesso em linha:https://biodiscovery.pensoft.net/article/8953/download/pdf/
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