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Targeting ATM pathway for therapeutic intervention in cancer
The Ataxia Telangiectasia Mutated gene encodes the ATM protein, a key element in the DNA damage response (DDR) signalling pathway responsible for maintaining genomic integrity within the cell. The ATM protein belongs to a family of large protein kinases containing the phosphatidylinositol-3 catalyti...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Pensoft Publishers
2012-07-01
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Colecção: | BioDiscovery |
Assuntos: | |
Acesso em linha: | https://biodiscovery.pensoft.net/article/8920/download/pdf/ |
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