From Concept to Clinical Product: A Brief History of the Novel <i>Shigella</i> Invaplex Vaccine’s Refinement and Evolution

The <i>Shigella</i> invasin complex or Invaplex vaccine is a unique subunit approach to generate a protective immune response. Invaplex is a large, macromolecular complex consisting of the major <i>Shigella</i> antigens: lipopolysaccharide (LPS) and the invasion plasmid antig...

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Main Authors: K. Ross Turbyfill, Kristen A. Clarkson, Edwin V. Oaks, Robert W. Kaminski
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-04-01
Series:Vaccines
Assuntos:
Invaplex
<i>Shigella</i>
vaccine
immunogenicity
adjuvant
antibody
Acceso en liña:https://www.mdpi.com/2076-393X/10/4/548
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