Generation of Inducible <i>BCL11B</i> Knockout in <i>TAL1/LMO1</i> Transgenic Mouse T Cell Leukemia/Lymphoma Model

The B-cell CLL/lymphoma 11B gene <i>(BCL11B</i>) plays a crucial role in T-cell development, but its role in T-cell malignancies is still unclear. To study its role in the development of T-cell neoplasms, we generated an inducible <i>BCL11B</i> knockout in a murine T cell leu...

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Main Authors: Grzegorz K. Przybylski, Dorota Korsak, Katarzyna Iżykowska, Karina Nowicka, Tomasz Zalewski, Małgorzata Tubacka, Maria Mosor, Danuta Januszkiewicz-Lewandowska, Magdalena Frydrychowicz, Maciej Boruczkowski, Grzegorz Dworacki, Jens van den Brandt, Piotr Grabarczyk, Christian A. Schmidt, Chengwu Zeng, Yangqiu Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:International Journal of Molecular Sciences
Assuntos:
BCL11B
TAL1
LMO1
CRE-ER/lox
T-ALL
TCL
Acesso em linha:https://www.mdpi.com/1422-0067/23/9/4932
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