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EBV-encoded LMP1 upregulates Igκ 3'enhancer activity and Igκ expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling.

Accumulating evidence indicates that epithelial cancer cells, including nasopharyngeal carcinoma (NPC) cells, express immunoglobulins (Igs). We previously found that the expression of the kappa light chain protein in NPC cells can be upregulated by the EBV-encoded latent membrane protein 1 (LMP1). I...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Haidan Liu, Zhi Duan, Hui Zheng, Duosha Hu, Ming Li, Yongguang Tao, Ann M Bode, Zigang Dong, Ya Cao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2012-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC3291551?pdf=render
Tagiau: Ychwanegu Tag
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