CD4+ T follicular helper and IgA+ B cell numbers in gut biopsies from HIV-infected subjects on antiretroviral therapy are comparable to HIV-uninfected individuals

Background: Disruption of gastrointestinal tract epithelial and immune barriers contribute to microbial translocation, systemic inflammation and progression of HIV-1 infection. Antiretroviral therapy (ART) may lead to reconstitution of CD4+ T cells in gastrointestinal-associated lymphoid tissue (GAL...

Full description

Saved in:
Bibliographic Details
Main Authors: John Zaunders, Mark Danta, Michelle Bailey, Gerald Mak, Katherine Marks, Nabila Seddiki, Yin Xu, David J Templeton, David A Cooper, Mark A Boyd, Anthony Dominic Kelleher, Kersten K Koelsch
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Immunology
Subjects:
HIV
Gut-associated lymphoid tissue
T follicular helper cells
CD4+ T lymphocytes
Germinal centres
IgA B cells
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00438/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items