Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells

High-risk neuroblastoma remains one of the deadliest childhood cancers. Identification of metabolic pathways that drive or maintain high-risk neuroblastoma may open new avenues of therapeutic interventions. Here, we report the isolation and propagation of neuroblastoma sphere-forming cells with self...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mengling Liu, Yingfeng Xia, Jane Ding, Bingwei Ye, Erhu Zhao, Jeong-Hyeon Choi, Ahmet Alptekin, Chunhong Yan, Zheng Dong, Shuang Huang, Liqun Yang, Hongjuan Cui, Yunhong Zha, Han-Fei Ding
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016-10-01
Collection:Cell Reports
Sujets:
cancer metabolism
cholesterol biosynthesis
high-risk neuroblastoma
mevalonate pathway
MYCN
neuroblastoma stem cells
serine-glycine biosynthesis
statin
TH-MYCN mouse
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2211124716312438
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires