Spontaneous Development of Dental Dysplasia in Aged <i>Parp-1</i> Knockout Mice

Poly(ADP-ribose) polymerase (Parp)-1 catalyzes polyADP-ribosylation using NAD<sup>+</sup> and is involved in the DNA damage response, genome stability, and transcription. In this study, we demonstrated that aged <i>Parp-1<sup>&#8722;/&#8722;</sup></i> mous...

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Main Authors: Hisako Fujihara, Tadashige Nozaki, Masahiro Tsutsumi, Mayu Isumi, Shinji Shimoda, Yoshiki Hamada, Mitsuko Masutani
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2019-09-01
Serija:Cells
Teme:
poly(adp-ribose) polymerase-1
aged mice
knockout mice
dental dysplasia
Online dostop:https://www.mdpi.com/2073-4409/8/10/1157
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