Synergetic Effects of PARP Inhibitor AZD2281 and Cisplatin in Oral Squamous Cell Carcinoma in Vitro and in Vivo

Cisplatin is a commonly used chemotherapeutic drug for treatment of oral carcinoma, and combinatorial effects are expected to exert greater therapeutic efficacy compared with monotherapy. Poly(ADP-ribosyl)ation is reported to be involved in a variety of cellular processes, such as DNA repair, cell d...

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Udgivet i:Int J Mol Sci
Main Authors: Yasukawa, Masaaki, Fujihara, Hisako, Fujimori, Hiroaki, Kawaguchi, Koji, Yamada, Hiroyuki, Nakayama, Ryoko, Yamamoto, Nanami, Kishi, Yuta, Hamada, Yoshiki, Masutani, Mitsuko
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813136/
https://ncbi.nlm.nih.gov/pubmed/26927065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17030272
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