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IFNγ and TNFα synergistically induce apoptosis of mesenchymal stem/stromal cells via the induction of nitric oxide

Abstract Background Mesenchymal stem/stromal cells (MSCs) have been widely used to treat various inflammatory diseases. The immunomodulatory capabilities of MSCs are usually licensed by inflammatory cytokines and may vary depending on the levels and the types of inflammatory cytokines. However, how...

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Bibliografische gegevens
Hoofdauteurs: Xiaolei Li, Bingxue Shang, Ya-nan Li, Yufang Shi, Changshun Shao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2019-01-01
Reeks:Stem Cell Research & Therapy
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Online toegang:http://link.springer.com/article/10.1186/s13287-018-1102-z
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