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Serine Biosynthesis Pathway Supports MYC–miR-494–EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells
Burkitt lymphoma (BL) is a rapidly growing tumor, characterized by high anabolic requirements. The <i>MYC</i> oncogene plays a central role in the pathogenesis of this malignancy, controlling genes involved in apoptosis, proliferation, and cellular metabolism. Serine biosynthesis pathway...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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MDPI AG
2020-03-01
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Schriftenreihe: | Cancers |
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Online Zugang: | https://www.mdpi.com/2072-6694/12/3/580 |
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