Serine Biosynthesis Pathway Supports MYC–miR-494–EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells

Burkitt lymphoma (BL) is a rapidly growing tumor, characterized by high anabolic requirements. The MYC oncogene plays a central role in the pathogenesis of this malignancy, controlling genes involved in apoptosis, proliferation, and cellular metabolism. Serine biosynthesis pathway (SBP) couples glyc...

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Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Białopiotrowicz, Emilia, Noyszewska-Kania, Monika, Kachamakova-Trojanowska, Neli, Łoboda, Agnieszka, Cybulska, Magdalena, Grochowska, Aleksandra, Kopczyński, Michał, Mikula, Michał, Prochorec-Sobieszek, Monika, Firczuk, Małgorzata, Graczyk-Jarzynka, Agnieszka, Zagożdżon, Radosław, Ząbek, Adam, Młynarz, Piotr, Dulak, Józef, Górniak, Patryk, Szydłowski, Maciej, Pyziak, Karolina, Martyka, Justyna, Sroka-Porada, Agnieszka, Jabłońska, Ewa, Polak, Anna, Kowalczyk, Piotr, Szumera-Ciećkiewicz, Anna, Chapuy, Bjoern, Rzymski, Tomasz, Brzózka, Krzysztof, Juszczyński, Przemysław
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139810/
https://ncbi.nlm.nih.gov/pubmed/32138178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030580
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