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In vitro and in silico Approaches to Study Cytochrome P450-Mediated Interactions

In vitro and in silico models of drug metabolism are utilized regularly in the drug research and development as tools for assessing pharmacokinetic variability and drug-drug interaction risk. The use of in vitro and in silico predictive approaches offers advantages including guiding rational design...

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Bibliographic Details
Main Authors: Boon Hooi Tan, Yan Pan, Amelia Nathania Dong, Chin Eng Ong
Format: Artigo
Language:Inglês
Published: Canadian Society for Pharmaceutical Sciences 2018-01-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/29323
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