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bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials

This paper presents the R package bcrm for conducting and assessing Bayesian continual reassessment method (CRM) designs in Phase I dose-escalation trials. CRM designsare a class of adaptive design that select the dose to be given to the next recruited patient based on accumulating toxicity data f...

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Bibliografiske detaljer
Main Authors: Michael Sweeting, Adrian Mander, Tony Sabin
Format: Artigo
Sprog:Inglês
Udgivet: Foundation for Open Access Statistics 2013-09-01
Serier:Journal of Statistical Software
Online adgang:http://www.jstatsoft.org/index.php/jss/article/view/2093
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