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Methodological Issues in the Clinical Validation of Biomarkers for Alzheimer’s Disease: The Paradigmatic Example of CSF

The use of biomarkers is profoundly transforming medical research and practice. Their adoption has triggered major advancements in the field of Alzheimer’s disease (AD) over the past years. For instance, the analysis of the cerebrospinal fluid (CSF) and neuroimaging changes indicative of neuronal lo...

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Hlavní autoři: Marco Canevelli, Ilaria Bacigalupo, Giuseppe Gervasi, Eleonora Lacorte, Marco Massari, Flavia Mayer, Nicola Vanacore, Matteo Cesari
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019-10-01
Edice:Frontiers in Aging Neuroscience
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On-line přístup:https://www.frontiersin.org/article/10.3389/fnagi.2019.00282/full
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