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Methodological Issues in the Clinical Validation of Biomarkers for Alzheimer’s Disease: The Paradigmatic Example of CSF

The use of biomarkers is profoundly transforming medical research and practice. Their adoption has triggered major advancements in the field of Alzheimer’s disease (AD) over the past years. For instance, the analysis of the cerebrospinal fluid (CSF) and neuroimaging changes indicative of neuronal lo...

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Détails bibliographiques
Publié dans:Front Aging Neurosci
Auteurs principaux: Canevelli, Marco, Bacigalupo, Ilaria, Gervasi, Giuseppe, Lacorte, Eleonora, Massari, Marco, Mayer, Flavia, Vanacore, Nicola, Cesari, Matteo
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812267/
https://ncbi.nlm.nih.gov/pubmed/31680936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00282
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