Methodological Issues in the Clinical Validation of Biomarkers for Alzheimer’s Disease: The Paradigmatic Example of CSF

The use of biomarkers is profoundly transforming medical research and practice. Their adoption has triggered major advancements in the field of Alzheimer’s disease (AD) over the past years. For instance, the analysis of the cerebrospinal fluid (CSF) and neuroimaging changes indicative of neuronal lo...

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Publicado en:Front Aging Neurosci
Autores principales: Canevelli, Marco, Bacigalupo, Ilaria, Gervasi, Giuseppe, Lacorte, Eleonora, Massari, Marco, Mayer, Flavia, Vanacore, Nicola, Cesari, Matteo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812267/
https://ncbi.nlm.nih.gov/pubmed/31680936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00282
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