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A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection

Inflammasome activation is associated with numerous diseases. However, in vivo detection of the activated inflammasome complex has been limited by a dearth of tools. We have developed transgenic mice that ectopically express the fluorescent adaptor protein, apoptosis-associated speck-like protein co...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Te-Chen Tzeng, Stefan Schattgen, Brian Monks, Donghai Wang, Anna Cerny, Eicke Latz, Katherine Fitzgerald, Douglas T. Golenbock
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2016-07-01
श्रृंखला:Cell Reports
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2211124716307306
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