Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration

The nonreducing disaccharide trehalose has been long considered only as a reserve carbohydrate. However, recent studies in yeast suggested that this osmolyte can protect cells and cellular proteins from oxidative damage elicited by exogenously added reactive oxygen species (ROS). Trehalose has been...

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Detaylı Bibliyografya
Asıl Yazarlar: Pavlo eKyryakov, Adam eBeach, Vincent R. Richard, Michelle T. Burstein, Anna eLeonov, Sean eLevy, Vladimir eTitorenko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2012-07-01
Seri Bilgileri:Frontiers in Physiology
Konular:
Caloric Restriction
Longevity
Trehalose
yeast
proteostasis
cellular aging
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00256/full
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