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Protein misfolding as an underlying molecular defect in mucopolysaccharidosis III type C.
Mucopolysaccharidosis type IIIC or Sanfilippo syndrome type C (MPS IIIC, MIM #252930) is an autosomal recessive disorder caused by deficiency of the lysosomal membrane enzyme, heparan sulfate acetyl-CoA: alpha-glucosaminide N-acetyltransferase (HGSNAT, EC 2.3.1.78), which catalyses transmembrane ace...
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Main Authors: | , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Public Library of Science (PLoS)
2009-10-01
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叢編: | PLoS ONE |
在線閱讀: | http://europepmc.org/articles/PMC2757673?pdf=render |
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