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Lower Circulating Leptin Levels Are Related to Non-Alcoholic Fatty Liver Disease in Children With Obesity

BackgroundWhile for individuals with obesity an association between hyperleptinemia and an increased risk of non-alcoholic fatty liver disease (NAFLD) is assumed, a leptin deficiency is also related to the development of NAFLD early in life in ob/ob mice, in patients with leptin deficiency due to bi...

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Detalhes bibliográficos
Main Authors: Stephanie Brandt, Julia von Schnurbein, Christian Denzer, Wolfgang Kratzer, Martin Wabitsch
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Endocrinology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2022.881982/full
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