miRNA-218 Targets Lipin-1 and Glucose Transporter Type 4 Genes in 3T3-L1 Cells Treated With Lopinavir/Ritonavir

Background: Metabolic complications represent a common and serious problem associated with HIV infection and combined Antiretroviral Therapy (cART). Alterations in body fat distribution are associated with significantly increased risks of (i) metabolic derangements, (ii) cardiovascular pathologies,...

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Main Authors: Elena Bresciani, Cecilia Saletti, Nicola Squillace, Laura Rizzi, Laura Molteni, Ramona Meanti, Robert J. Omeljaniuk, Giuseppe Biagini, Andrea Gori, Vittorio Locatelli, Antonio Torsello
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-04-01
Colecção:Frontiers in Pharmacology
Assuntos:
HIV protease inhibitors
lipodystrophy
miRNA
adipocyte
insulin resistance
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2019.00461/full
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