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Interaction between lopinavir/ritonavir and warfarin

Drug interactions involving protease inhibitors are common. Protease inhibitors are well known inhibitors of the 3A4 isozyme of cytochrome P450. Select protease inhibitors, including co-formulated lopinavir/ritonavir, may induce glucuronidation or the activity of other CYP450 isozymes. We describe t...

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Bibliografiske detaljer
Main Authors: Hughes, Christine A., Freitas, Andrea, Miedzinski, Lilly J.
Format: Artigo
Sprog:Inglês
Udgivet: Canadian Medical Association 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1942099/
https://ncbi.nlm.nih.gov/pubmed/17698824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.061284
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