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Ablation of the Cl-/HCO3- Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis

Background/Aims: The Cl-/HCO3- exchanger pendrin and the thiazide-sensitive Na-Cl cotransporter NCC are expressed in the kidney distal nephron and mediate salt absorption. We hypothesized that deletion of pendrin leaves NCC as the major salt absorbing transporter in the distal nephron and therefore...

詳細記述

保存先:
書誌詳細
主要な著者: Saeed Alshahrani, Manoocher Soleimani
フォーマット: Artigo
言語:Inglês
出版事項: Karger Publishers 2017-07-01
シリーズ:Kidney & Blood Pressure Research
主題:
NCC
オンライン・アクセス:http://www.karger.com/Article/FullText/479296
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