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Ablation of the Cl-/HCO3- Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis
Background/Aims: The Cl-/HCO3- exchanger pendrin and the thiazide-sensitive Na-Cl cotransporter NCC are expressed in the kidney distal nephron and mediate salt absorption. We hypothesized that deletion of pendrin leaves NCC as the major salt absorbing transporter in the distal nephron and therefore...
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主要な著者: | , |
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フォーマット: | Artigo |
言語: | Inglês |
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Karger Publishers
2017-07-01
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シリーズ: | Kidney & Blood Pressure Research |
主題: | |
オンライン・アクセス: | http://www.karger.com/Article/FullText/479296 |
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