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A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs

G protein-coupled receptors (GPCRs) play a key role in many cellular signaling mechanisms, and must select among multiple coupling possibilities in a ligand-specific manner in order to carry out a myriad of functions in diverse cellular contexts. Much has been learned about the molecular mechanisms...

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Bibliografiske detaljer
Main Authors: Ambrose Plante, Derek M. Shore, Giulia Morra, George Khelashvili, Harel Weinstein
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-06-01
Serier:Molecules
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Online adgang:https://www.mdpi.com/1420-3049/24/11/2097
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