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Chemical Structure-Related Drug-Like Criteria of Global Approved Drugs

The chemical structure of a drug determines its physicochemical properties, further determines its ADME/Tox properties, and ultimately affects its pharmacological activity. Medicinal chemists can regulate the pharmacological activity of drug molecules by modifying their structure. Ring systems and f...

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Detalhes bibliográficos
Main Authors: Fei Mao, Wei Ni, Xiang Xu, Hui Wang, Jing Wang, Min Ji, Jian Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2016-01-01
Colecção:Molecules
Assuntos:
Acesso em linha:http://www.mdpi.com/1420-3049/21/1/75
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