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Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery

The melting point (MP), an easily accessible physical parameter, has considerable potential for the judgment of drug‐like properties. However, to the best of our knowledge, there are no useful guidelines for understanding the relationship between the MP and drug‐like properties. To this end, we have...

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Detalhes bibliográficos
Publicado no:ChemistryOpen
Main Authors: Mao, Fei, Kong, Qingya, Ni, Wei, Xu, Xiang, Ling, Dazheng, Lu, Zhengyu, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981057/
https://ncbi.nlm.nih.gov/pubmed/27547646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201600015
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