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ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia

Summary: Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary epithelia are associated with dysregulated Wnt/β-catenin signaling in chronic airway diseases, but underlying mechanisms remain elusive, and studies yield seemingly c...

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Detalhes bibliográficos
Main Authors: Maximilian Haas, José Luis Gómez Vázquez, Dingyuan Iris Sun, Hong Thi Tran, Magdalena Brislinger, Alexia Tasca, Orr Shomroni, Kris Vleminckx, Peter Walentek
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019-09-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124719311180
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