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Impaired ΔNp63 expression associates with reduced β-catenin and aggressive phenotypes of urothelial neoplasms

p63, a homologue of the p53 gene, is considered to be essential for the normal development of stratified epithelia including urothelium. To examine possible roles of p63 in urothelial tumorigenesis, p63 expression was systematically examined in normal urothelium, low-grade papillary noninvasive (LPN...

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Bibliografiske detaljer
Main Authors: Koga, F, Kawakami, S, Kumagai, J, Takizawa, T, Ando, N, Arai, G, Kageyama, Y, Kihara, K
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376335/
https://ncbi.nlm.nih.gov/pubmed/12618884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600764
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