Elevated α-Ketoglutaric Acid Concentrations and a Lipid-Balanced Signature Are the Key Factors in Long-Term HIV Control

Long-term elite controllers (LTECs) are a fascinating small subset of HIV individuals with viral and immunological HIV control in the long term that have been designated as models of an HIV functional cure. However, data on the LTEC phenotype are still scarce, and hence, the metabolomics and lipidom...

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Главные авторы: Jenifer Masip, Norma Rallón, Elena Yeregui, Montserrat Olona, Salvador Resino, José M. Benito, Consuelo Viladés, Graciano García-Pardo, José Alcamí, Ezequiel Ruiz-Mateos, Frederic Gómez-Bertomeu, Montserrat Vargas, Marta Navarro, José A. Oteo, Juan A. Pineda, Anna Martí, Verónica Alba, Francesc Vidal, Joaquin Peraire, Anna Rull
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2022-04-01
Серии:Frontiers in Immunology
Предметы:
metabolomics
lipidomics
elite controllers (ECs)
HIV infection
Kreb's cycle
long-term
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fimmu.2022.822272/full
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